HitPredict

Interactor 1: Q7KJ69 (Q7KJ69)
GEO01805p1 (IP02725p) (SKP1-related B) (SKPB)
Gene: SkpB

Interactor 2: FBSP1 (Q9V6L9)
F-box/SPRY domain-containing protein 1 (DFsn)
Gene: Fsn

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	14605208, 15575970, 22036573
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	F-box-like~Skp1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 161 Dm			1 255
+	Dm
		285009 O77430_DROME (1-161): 1.33e-81: 239: 72.84		FBSP1_DROME (1-255): 3.89e-118: 339: 100.00
+	Hs
		472696 SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49		FBSP1_HUMAN (13-255): 5.33e-104: 305: 71.31
+	Ce
		105470 SKR1_CAEEL (4-160): 1.21e-79: 235: 60.25		FBSP1_CAEEL (13-255): 1.1e-101: 300: 56.56
+	Dm
		51275 Q7KJ69_DROME (1-161): 1.07e-78: 232: 100.00		GUS_DROME (58-250): 1.17e-70: 219: 41.92
+	Hs
		928959 SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49		TRI67_HUMAN (74-246): 6.16e-37: 139: 18.64
+	Hs
		928989 SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49		SPRY3_HUMAN (109-203): 4.91e-10: 60.9: 13.54