Interactor 1: Q7KLI1 (Q7KLI1)
Apaf-1 related killer DARK (Apaf-1/CED-4-related caspase activator Dapaf-1L) (Cell death protein HAC-1) (Death-associated APAF1-related killer, isoform B) (FI21208p1)
Gene: Dark

Interactor 2: Q7KLI1 (Q7KLI1)
Apaf-1 related killer DARK (Apaf-1/CED-4-related caspase activator Dapaf-1L) (Cell death protein HAC-1) (Death-associated APAF1-related killer, isoform B) (FI21208p1)
Gene: Dark

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.666

The method score is based on:

Property Details
Experiments 21220123
Identification Methods cosedimentation through density gradient, 3D electron microscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains APAF1_C~NB-ARC, NB-ARC~NB-ARC
Common GO terms GO:0002921 - negative regulation of humoral immune response
GO:0005524 - ATP binding
GO:0007291 - sperm individualization
GO:0008656 - cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0010332 - response to gamma radiation
and 18 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1440
Dm

1 1440
+ Dm

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Last updated: 15 Jul 2024