HitPredict

Interactor 1: Q7KLI1 (Q7KLI1)
Apaf-1 related killer DARK (Apaf-1/CED-4-related caspase activator Dapaf-1L) (Cell death protein HAC-1) (Death-associated APAF1-related killer, isoform B) (FI21208p1)
Gene: Dark

Interactor 2: DRONC (Q9XYF4)
Caspase Dronc (EC 3.4.22.-) (NEDD2-like caspase) [Cleaved into: Caspase Nc subunit 1; Caspase Nc subunit 2]
Gene: DRONC

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

The method score is based on:

Property	Details
Experiments	21220123, 20700104
Identification Methods	cosedimentation through density gradient, 3D electron microscopy, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007291 - sperm individualization GO:0012501 - programmed cell death GO:0022416 - chaeta development GO:0035006 - melanization defense response GO:0035070 - salivary gland histolysis and 5 others more... GO:0043065 - positive regulation of apoptotic process GO:0043293 - apoptosome GO:0046672 - positive regulation of compound eye retinal cell programmed cell death GO:0048813 - dendrite morphogenesis GO:0050700 - CARD domain binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	1440
Dm

1	450

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024