HitPredict

Interactor 1: PSD11 (Q7KLV9)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory complex subunit p42B) (26S proteasome regulatory subunit Rpn6)
Gene: Rpn6

Interactor 2: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005838 - proteasome regulatory particle GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 422 Dm			1 433
+	Hs
		121699 PSD11_HUMAN (2-422): 4.23e-110: 332: 67.93		PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69
+	Dm
		186117 PSD11_DROME (1-422): 1.49e-115: 345: 100.00		PRS8_DROME (50-430): 1.1e-124: 369: 48.56
+	Dm
		820482 PSD11_DROME (1-422): 1.49e-115: 345: 100.00		PRS4_DROME (1-430): 3.22e-118: 353: 38.89
+	Dm
		1180716 PSD11_DROME (1-422): 1.49e-115: 345: 100.00		Q9V405_DROME (29-425): 4.38e-118: 352: 37.87
+	Dm
		1180728 PSD11_DROME (1-422): 1.49e-115: 345: 100.00		Q9W414_DROME (33-429): 1.01e-116: 348: 43.00
+	Hs
		121727 PSD11_HUMAN (2-422): 4.23e-110: 332: 67.93		PRS8_HUMAN (27-430): 2.52e-121: 360: 45.79
+	Hs
		730263 PSMD6_HUMAN (33-415): 8.07e-87: 271: 14.54		PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69
+	Hs
		121729 PSD11_HUMAN (2-422): 4.23e-110: 332: 67.93		PRS10_HUMAN (34-429): 5.68e-118: 351: 41.86
+	Hs
		121726 PSD11_HUMAN (2-422): 4.23e-110: 332: 67.93		PRS4_HUMAN (1-430): 1e-116: 349: 40.28
+	Hs
		897226 CSN2_HUMAN (14-419): 7.35e-93: 288: 19.63		PRS8_HUMAN (27-430): 2.52e-121: 360: 45.79
+	Sc
		703976 RPN6_YEAST (38-421): 3.56e-83: 263: 47.04		PRS7_YEAST (1-433): 9.76e-128: 379: 67.24
+	Hs
		897225 CSN2_HUMAN (14-419): 7.35e-93: 288: 19.63		PRS4_HUMAN (1-430): 1e-116: 349: 40.28
+	Hs
		907033 PSMD6_HUMAN (33-415): 8.07e-87: 271: 14.54		PRS8_HUMAN (27-430): 2.52e-121: 360: 45.79
+	Dm
		186130 PSMD6_DROME (33-415): 1.12e-80: 255: 14.50		PRS8_DROME (50-430): 1.1e-124: 369: 48.56
+	Hs
		913268 PSMD6_HUMAN (33-415): 8.07e-87: 271: 14.54		PRS10_HUMAN (34-429): 5.68e-118: 351: 41.86
+	Hs
		906832 PSMD6_HUMAN (33-415): 8.07e-87: 271: 14.54		PRS4_HUMAN (1-430): 1e-116: 349: 40.28
+	Sc
		968100 RPN6_YEAST (38-421): 3.56e-83: 263: 47.04		PRS8_YEAST (43-430): 4.52e-117: 349: 45.36
+	Dm
		820500 PSMD6_DROME (33-415): 1.12e-80: 255: 14.50		PRS4_DROME (1-430): 3.22e-118: 353: 38.89
+	Dm
		1358526 PSMD6_DROME (33-415): 1.12e-80: 255: 14.50		Q9V405_DROME (29-425): 4.38e-118: 352: 37.87
+	Dm
		1358538 PSMD6_DROME (33-415): 1.12e-80: 255: 14.50		Q9W414_DROME (33-429): 1.01e-116: 348: 43.00