HitPredict

Interactor 1: NITO (Q7KMJ6)
RNA-binding protein spenito
Gene: NITO

Interactor 2: LARP (Q9VAW5)
La-related protein 1 (dLarp)
Gene: LARP

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 29555755
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 793 Dm			1 1673
+	Dm
		597071 PABP_DROME (1-324): 3.41e-34: 141: 11.70		LARP_DROME (1-1673): 0: 909: 100.00
+	Hs
		474033 PAB4L_HUMAN (1-269): 7.37e-41: 155: 11.93		LAR4B_HUMAN (565-1284): 6.38e-81: 285: 13.91
+	Hs
		1268142 PABP5_HUMAN (1-284): 9.83e-36: 141: 12.00		LAR4B_HUMAN (565-1284): 6.38e-81: 285: 13.91
+	Hs
		1031407 PABP4_HUMAN (14-242): 4.69e-30: 128: 12.03		LAR4B_HUMAN (565-1284): 6.38e-81: 285: 13.91
+	Sc
		376965 PABP_YEAST (1-303): 4.06e-37: 149: 14.73		SLF1_YEAST (468-789): 9.47e-49: 183: 20.35
+	Hs
		1174835 PABP5_HUMAN (1-284): 9.83e-36: 141: 12.00		LARP4_HUMAN (621-1284): 3.91e-46: 181: 12.57
+	At
		790116 PABP2_ARATH (1-310): 2.46e-37: 150: 13.50		LRP6C_ARATH (692-1067): 5.48e-35: 142: 15.98
+	At
		285476 PABP2_ARATH (1-310): 2.46e-37: 150: 13.50		LRP6B_ARATH (686-1068): 3.18e-34: 141: 15.06
+	Sc
		376650 PABP_YEAST (1-303): 4.06e-37: 149: 14.73		SRO9_YEAST (462-789): 1.66e-29: 125: 18.13
+	Hs
		1162644 PABP5_HUMAN (1-284): 9.83e-36: 141: 12.00		LARP1_HUMAN (322-1200): 1.96e-25: 116: 14.05
+	Hs
		1031352 PABP4_HUMAN (14-242): 4.69e-30: 128: 12.03		LARP7_HUMAN (727-1221): 1e-29: 128: 12.09
+	Hs
		403212 PABP4_HUMAN (14-242): 4.69e-30: 128: 12.03		LA_HUMAN (729-943): 1.61e-30: 128: 18.47
+	Hs
		1116304 PAP1L_HUMAN (14-248): 5.22e-28: 122: 10.98		LARP7_HUMAN (727-1221): 1e-29: 128: 12.09
+	Hs
		1116542 PABP3_HUMAN (304-551): 5.25e-28: 122: 16.79		LARP7_HUMAN (727-1221): 1e-29: 128: 12.09
+	Hs
		516541 PABP1_HUMAN (14-310): 4.59e-28: 122: 11.58		LARP7_HUMAN (727-1221): 1e-29: 128: 12.09
+	Hs
		1031367 PABP4_HUMAN (14-242): 4.69e-30: 128: 12.03		LARP1_HUMAN (322-1200): 1.96e-25: 116: 14.05
+	Sc
		376709 PABP_YEAST (1-303): 4.06e-37: 149: 14.73		LHP1_YEAST (700-853): 9.26e-18: 87.4: 23.08
+	Hs
		1145698 PABP5_HUMAN (1-284): 9.83e-36: 141: 12.00		LAR1B_HUMAN (560-1158): 1.63e-13: 78.1: 12.56
+	Hs
		516553 PABP1_HUMAN (14-310): 4.59e-28: 122: 11.58		LAR1B_HUMAN (560-1158): 1.63e-13: 78.1: 12.56
+	Hs
		1031405 PABP4_HUMAN (14-242): 4.69e-30: 128: 12.03		TITIN_HUMAN (8-853): 1.12e-09: 66.1: 9.20