HitPredict

Interactor 1: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Interactor 2: PSA6 (Q9XZJ4)
Proteasome subunit alpha type-6 (20S proteasome subunit alpha-1)
Gene: Prosalpha1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA~Proteasome_A_N, AAA_lid_3~Proteasome, AAA_lid_3~Proteasome_A_N
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Dm			1 244
+	Hs
		637639 PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69		PSA2_HUMAN (7-241): 4.45e-107: 310: 32.34
+	Dm
		771298 Q7KMQ0_DROME (1-433): 3.2e-145: 422: 100.00		PSA2_DROME (8-240): 1.18e-104: 304: 30.04
+	Hs
		730228 PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69		PSA6_HUMAN (1-244): 1.47e-103: 301: 66.67
+	Dm
		1181022 Q7KMQ0_DROME (1-433): 3.2e-145: 422: 100.00		PSA5_DROME (1-241): 1.83e-96: 283: 27.02
+	Hs
		656158 PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69		PSA5_HUMAN (1-240): 7.67e-97: 284: 28.57
+	Hs
		638074 PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69		PSA4_HUMAN (6-237): 1.53e-93: 276: 29.11
+	Hs
		156240 PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69		PSA7_HUMAN (9-238): 2.6e-92: 273: 31.03
+	Dm
		186105 PRS8_DROME (50-430): 1.1e-124: 369: 48.56		PSA2_DROME (8-240): 1.18e-104: 304: 30.04
+	Sp
		194879 PRS7_SCHPO (1-430): 5.44e-132: 388: 72.81		PSA5_SCHPO (1-243): 9.74e-96: 281: 26.51
+	Dm
		186173 PRS8_DROME (50-430): 1.1e-124: 369: 48.56		PSA6_DROME (1-244): 2.55e-102: 298: 100.00
+	Dm
		186129 PRS8_DROME (50-430): 1.1e-124: 369: 48.56		PSA5_DROME (1-241): 1.83e-96: 283: 27.02
+	Sc
		689167 PRS7_YEAST (1-433): 9.76e-128: 379: 67.24		PSA5_YEAST (1-244): 7e-91: 270: 25.60
+	Sc
		597306 PRS7_YEAST (1-433): 9.76e-128: 379: 67.24		PSA1_YEAST (9-244): 1.85e-73: 225: 48.56
+	Ce
		184351 PRS10_CAEEL (30-426): 2.08e-157: 452: 44.25		PSA2_CAEEL (4-237): 3.24e-34: 124: 31.06
+	Sp
		144489 PRS6A_SCHPO (22-431): 1.15e-151: 438: 36.74		PSA4_SCHPO (7-204): 7.45e-35: 126: 34.17
+	Dm
		1181031 Q7KMQ0_DROME (1-433): 3.2e-145: 422: 100.00		PSA3_DROME (8-242): 5.22e-33: 122: 30.51
+	Sc
		619347 PRS7_YEAST (1-433): 9.76e-128: 379: 67.24		PSA3_YEAST (6-201): 1.95e-42: 146: 39.09
+	Sp
		194877 PRS7_SCHPO (1-430): 5.44e-132: 388: 72.81		PSA4_SCHPO (7-204): 7.45e-35: 126: 34.17
+	Sc
		619440 PRS7_YEAST (1-433): 9.76e-128: 379: 67.24		PSA2_YEAST (13-237): 2.06e-34: 125: 31.54
+	Dm
		186137 PRS8_DROME (50-430): 1.1e-124: 369: 48.56		PSA3_DROME (8-242): 5.22e-33: 122: 30.51