HitPredict

Interactor 1: Q7KS72 (Q7KS72)
C15 (FI01111p)
Gene: C15

Interactor 2: TRR (Q8IRW8)
Histone-lysine N-methyltransferase trr (EC 2.1.1.354) (Lysine N-methyltransferase 2C) (Trithorax-related protein)
Gene: TRR

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	30995488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Dm			1 2431
+	Dm
		1215698 Q8MZ02_DROME (216-281): 3.11e-13: 71.6: 48.49		TRR_DROME (1-2431): 0: 1724: 100.00
+	Hs
		213370 TLX2_HUMAN (62-337): 1.34e-32: 124: 38.77		EHMT2_HUMAN (1761-2427): 3.63e-102: 361: 16.50
+	Hs
		1296426 VSX1_HUMAN (47-325): 2.62e-31: 122: 17.92		EHMT2_HUMAN (1761-2427): 3.63e-102: 361: 16.50
+	Hs
		679157 TLX1_HUMAN (150-334): 7.69e-31: 120: 54.05		EHMT2_HUMAN (1761-2427): 3.63e-102: 361: 16.50
+	Hs
		211935 TLX3_HUMAN (63-335): 1e-30: 119: 38.57		EHMT2_HUMAN (1761-2427): 3.63e-102: 361: 16.50
+	Hs
		595604 HXA5_HUMAN (175-288): 3.34e-34: 128: 29.83		EZH2_HUMAN (1976-2412): 2.41e-78: 279: 16.60
+	Hs
		213385 TLX2_HUMAN (62-337): 1.34e-32: 124: 38.77		EHMT1_HUMAN (1702-2427): 1.18e-72: 270: 14.79
+	Hs
		1334136 VSX1_HUMAN (47-325): 2.62e-31: 122: 17.92		EHMT1_HUMAN (1702-2427): 1.18e-72: 270: 14.79
+	Hs
		679173 TLX1_HUMAN (150-334): 7.69e-31: 120: 54.05		EHMT1_HUMAN (1702-2427): 1.18e-72: 270: 14.79
+	Hs
		211969 TLX3_HUMAN (63-335): 1e-30: 119: 38.57		EHMT1_HUMAN (1702-2427): 1.18e-72: 270: 14.79
+	Hs
		678902 HXC8_HUMAN (123-285): 7.88e-35: 129: 22.75		KMT2A_HUMAN (1892-2224): 4.37e-61: 236: 26.35
+	Hs
		152582 HXB2_HUMAN (186-326): 6.53e-37: 137: 30.41		KMT2D_HUMAN (72-1348): 4.99e-09: 64.5: 8.96
+	Hs
		213358 TLX2_HUMAN (62-337): 1.34e-32: 124: 38.77		KMT2C_HUMAN (1905-2177): 5.73e-11: 70.6: 14.23
+	Hs
		679137 TLX1_HUMAN (150-334): 7.69e-31: 120: 54.05		KMT2C_HUMAN (1905-2177): 5.73e-11: 70.6: 14.23
+	Hs
		211919 TLX3_HUMAN (63-335): 1e-30: 119: 38.57		KMT2C_HUMAN (1905-2177): 5.73e-11: 70.6: 14.23
+	Hs
		152561 TLX2_HUMAN (62-337): 1.34e-32: 124: 38.77		KMT2D_HUMAN (72-1348): 4.99e-09: 64.5: 8.96
+	Hs
		882142 GSC_HUMAN (78-301): 3.81e-30: 117: 18.10		KMT2C_HUMAN (1905-2177): 5.73e-11: 70.6: 14.23
+	Hs
		152596 TLX1_HUMAN (150-334): 7.69e-31: 120: 54.05		KMT2D_HUMAN (72-1348): 4.99e-09: 64.5: 8.96
+	Hs
		152560 TLX3_HUMAN (63-335): 1e-30: 119: 38.57		KMT2D_HUMAN (72-1348): 4.99e-09: 64.5: 8.96
+	Hs
		152620 GSC_HUMAN (78-301): 3.81e-30: 117: 18.10		KMT2D_HUMAN (72-1348): 4.99e-09: 64.5: 8.96