Interactor 1: PRKN (Q7KTX7)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31)
Gene: park

Interactor 2: PRKN (Q7KTX7)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31)
Gene: park

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 17456438, 29689197
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ubiquitin~ubiquitin, ubiquitin~zf-RING_12, ubiquitin~zf-RING_14, zf-RING_12~zf-RING_12, zf-RING_12~zf-RING_14
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0000266 - mitochondrial fission
GO:0000422 - autophagy of mitochondrion
GO:0001933 - negative regulation of protein phosphorylation
and 34 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 482
Dm

1 482
+ Hs
+ Rn
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024