Interactor 1: PRKN (Q7KTX7)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31)
Gene: park

Interactor 2: ARI1 (Q94981)
E3 ubiquitin-protein ligase ariadne-1 (EC 2.3.2.31) (Protein ariadne-1) (RING-type E3 ubiquitin transferase ariadne-1)
Gene: ari-1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29689197
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ariadne~ubiquitin, IBR~ubiquitin, ubiquitin~zf-C3HC4, IBR~zf-RING_12, IBR~zf-RING_14
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 7 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 482
Dm

1 503
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Zm
+ At
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024