HitPredict

Interactor 1: SPT6H (Q7KZ85)
Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein)
Gene: SUPT6H

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1726 Hs			1 427
+	Hs
		1182943 SPT6H_HUMAN (1-1726): 0: 1802: 100.00		SNR40_HUMAN (272-427): 1.08e-24: 106: 12.58
+	Hs
		921625 SPT6H_HUMAN (1-1726): 0: 1802: 100.00		GBB2_HUMAN (217-427): 9.72e-19: 88.6: 15.57
+	Hs
		1234299 SRBD1_HUMAN (218-1212): 0: 597: 16.76		SNR40_HUMAN (272-427): 1.08e-24: 106: 12.58
+	Hs
		1334032 MDN1_HUMAN (6-680): 7.05e-92: 335: 12.40		WDR76_HUMAN (114-412): 2.61e-81: 264: 23.89
+	Hs
		1345855 MDN1_HUMAN (6-680): 7.05e-92: 335: 12.40		NLE1_HUMAN (279-427): 4.77e-30: 123: 16.77
+	Sc
		630897 MDN1_YEAST (7-602): 7.28e-20: 99.7: 12.98		NLE1_YEAST (232-426): 6.78e-39: 148: 17.77
+	Sp
		252177 MDN1_SCHPO (1-357): 4.01e-13: 77.3: 13.54		NLE1_SCHPO (10-140): 6.66e-21: 96.8: 11.45