HitPredict

Interactor 1: SPT6H (Q7KZ85)
Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein)
Gene: SUPT6H

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1726 Hs			1 456
+	Hs
		1182978 SPT6H_HUMAN (1-1726): 0: 1802: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		1329375 SLK_HUMAN (1-526): 6.05e-33: 142: 11.15		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		1329374 SLK_HUMAN (1-526): 6.05e-33: 142: 11.15		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Sc
		978037 MDN1_YEAST (7-602): 7.28e-20: 99.7: 12.98		RUVB1_YEAST (1-455): 0: 652: 67.39
+	Dm
		1341931 DOM_DROME (78-402): 1.77e-11: 71.9: 15.20		RUVB1_DROME (1-455): 0: 660: 79.56
+	Hs
		1261249 LEO1_HUMAN (1-345): 1.27e-13: 78.1: 13.68		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Sc
		1014863 MDN1_YEAST (7-602): 7.28e-20: 99.7: 12.98		RUVB2_YEAST (5-455): 0: 627: 41.72
+	Mm
		1140415 LEO1_MOUSE (24-312): 4.33e-11: 70: 14.80		RUVB2_MOUSE (2-455): 0: 651: 42.76