HitPredict

Interactor 1: HAX1 (O00165)
HCLS1-associated protein X-1 (HS1-associating protein X-1) (HAX-1) (HS1-binding protein 1) (HSP1BP-1)
Gene: HAX1

Interactor 2: DPYL3 (Q14195)
Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1)
Gene: DPYSL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030027 - lamellipodium GO:0071345 - cellular response to cytokine stimulus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 279 Hs			1 570
+	Hs
		118303 HAX1_HUMAN (1-279): 0: 502: 100.00		DPYL1_HUMAN (1-569): 0: 748: 74.43
+	Hs
		118325 HAX1_HUMAN (1-279): 0: 502: 100.00		DPYL2_HUMAN (1-569): 0: 742: 76.71
+	Hs
		118103 HAX1_HUMAN (1-279): 0: 502: 100.00		DPYL4_HUMAN (1-570): 0: 730: 70.11
+	Hs
		118423 HAX1_HUMAN (1-279): 0: 502: 100.00		DPYL5_HUMAN (9-565): 0: 649: 50.71
+	Hs
		118207 HAX1_HUMAN (1-279): 0: 502: 100.00		PYR1_HUMAN (26-562): 1.21e-133: 431: 17.65