HitPredict

Interactor 1: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Interactor 2: RAI14 (Q9P0K7)
Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14)
Gene: RAI14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras, Ank_4~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Hs			1 980
+	Hs
		1268073 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		892642 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		RAI14_HUMAN (1-980): 4.28e-77: 274: 100.00
+	Hs
		951418 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		RAI14_HUMAN (1-980): 4.28e-77: 274: 100.00
+	Hs
		1183487 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		892521 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		1021421 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		ANK3_HUMAN (24-405): 2.11e-47: 187: 18.74
+	Hs
		950953 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		ANK3_HUMAN (24-405): 2.11e-47: 187: 18.74
+	Hs
		892575 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		UACA_HUMAN (411-974): 2.3e-39: 161: 24.63
+	Hs
		951304 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		UACA_HUMAN (411-974): 2.3e-39: 161: 24.63
+	Hs
		436267 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		980507 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		436568 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		KDIS_HUMAN (160-403): 1.98e-12: 73.9: 16.39
+	Hs
		1296761 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		KDIS_HUMAN (160-403): 1.98e-12: 73.9: 16.39
+	Hs
		980421 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		892331 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		950942 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		1183607 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		KDIS_HUMAN (160-403): 1.98e-12: 73.9: 16.39
+	Hs
		892676 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		KDIS_HUMAN (160-403): 1.98e-12: 73.9: 16.39
+	Hs
		951454 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		KDIS_HUMAN (160-403): 1.98e-12: 73.9: 16.39
+	Hs
		925219 RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61