HitPredict

Interactor 1: EIF3M (Q7L2H7)
Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1)
Gene: EIF3M

Interactor 2: EIF3L (Q9Y262)
Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein)
Gene: EIF3L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.964

The method score is based on:

Property Details
Experiments 26186194, 17403899, 28514442, 24981860, 33961781, 35271311, 23623729
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~Paf67
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005852 - eukaryotic translation initiation factor 3 complex
GO:0006413 - translational initiation
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 374
Hs

1 564
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024