HitPredict

Interactor 1: CYFP1 (Q7L576)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
Gene: CYFIP1

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1253 Hs			1 236
+	Hs
		1183433 CYFP1_HUMAN (1-1253): 0: 2086: 100.00		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		951104 CYFP1_HUMAN (1-1253): 0: 2086: 100.00		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		925386 CYFP1_HUMAN (1-1253): 0: 2086: 100.00		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		892449 CYFP1_HUMAN (1-1253): 0: 2086: 100.00		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Mm
		925800 CYFP1_MOUSE (1-1253): 0: 2079: 99.04		RAC1_MOUSE (32-217): 3.34e-76: 230: 53.23
+	Hs
		545463 CYFP1_HUMAN (1-1253): 0: 2086: 100.00		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		900624 CYFP1_HUMAN (1-1253): 0: 2086: 100.00		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		951231 CYFP2_HUMAN (1-1253): 0: 2070: 85.92		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		925513 CYFP2_HUMAN (1-1253): 0: 2070: 85.92		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		892535 CYFP2_HUMAN (1-1253): 0: 2070: 85.92		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		545555 CYFP2_HUMAN (1-1253): 0: 2070: 85.92		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		894162 CYFP1_HUMAN (1-1253): 0: 2086: 100.00		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		900789 CYFP2_HUMAN (1-1253): 0: 2070: 85.92		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		1184655 CYFP1_HUMAN (1-1253): 0: 2086: 100.00		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27
+	Dm
		776913 CYFIP_DROME (1-1253): 0: 1903: 65.73		RAC1_DROME (32-217): 4.08e-74: 224: 53.76
+	At
		1105123 PIR_ARATH (5-1240): 0: 1535: 28.88		RAC3_ARATH (27-209): 1.49e-72: 220: 47.00
+	At
		1105134 PIR_ARATH (5-1240): 0: 1535: 28.88		RAC4_ARATH (32-202): 7.2e-58: 183: 50.29
+	At
		1105104 PIR_ARATH (5-1240): 0: 1535: 28.88		RAC1_ARATH (32-202): 2.11e-57: 182: 50.87