Interactor 1: CYFP1 (Q7L576)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
Gene: CYFIP1

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Abi_HHR~FragX_IP
Common GO terms GO:0005829 - cytosol
GO:0010592 - positive regulation of lamellipodium assembly
GO:0016601 - Rac protein signal transduction
GO:0030027 - lamellipodium
GO:0031209 - SCAR complex
and 3 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1253
Hs

1 513
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Dm
+ Dd

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Last updated: 15 Jul 2024