Interactor 1: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6

Interactor 2: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 25242525, 32034103, 21145461
Identification Methods x-ray crystallography, pull down, affinity chromatography technology
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~JAB, JAB~MitMem_reg, MitMem_reg~MitMem_reg
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 327
Hs

1 327
+ Dm
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Dm
+ Dm
+ Ce
+ Sp
+ Ce
+ Ce

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Last updated: 15 Jul 2024