HitPredict

Interactor 1: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6

Interactor 2: KLDC3 (Q9BQ90)
Kelch domain-containing protein 3 (Testis intracellular mediator protein)
Gene: KLHDC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 382
+	Hs
		299521 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH18_HUMAN (3-247): 6.9e-42: 156: 16.33
+	Hs
		1120774 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH12_HUMAN (1-191): 4.3e-40: 151: 18.33
+	Hs
		1185001 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH13_HUMAN (140-381): 1.58e-39: 150: 15.39
+	Hs
		1185018 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH20_HUMAN (2-189): 1.45e-36: 142: 18.62
+	Hs
		1153783 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH10_HUMAN (2-190): 6.04e-33: 131: 17.46
+	Hs
		1184999 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLHL9_HUMAN (1-188): 2.78e-31: 127: 14.58
+	Hs
		1184998 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLHL8_HUMAN (1-136): 8.04e-20: 93.2: 19.12