Interactor 1: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6
Interactor 2: CSN4 (Q9BT78)
COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)
Gene: COPS4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 31444342, 32034103, 36652389, 19141280, 19295130, 23086934, 26186194, 28514442, 27173435, 33961781, 19615732, 21145461, 25043011, unassigned1304 |
| Identification Methods | two hybrid, pull down, cross-linking study, affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CSN4_RPN5_eIF3a~JAB, JAB~PCI, CSN4_RPN5_eIF3a~MitMem_reg, MitMem_reg~PCI |
| Common GO terms | GO:0000338 - protein deneddylation GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 3 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
