HitPredict - High confidence protein-protein interactions

Interactor 1: CHM1B (Q7LBR1)
Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2)
Gene: CHMP1B

Interactor 2: CHM1A (Q9HD42)
Charged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a) (Vacuolar protein sorting-associated protein 46-1) (Vps46-1) (hVps46-1)
Gene: CHMP1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	33961781, 14505570, 16730941
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0000421 - autophagosome membrane GO:0000776 - kinetochore GO:0000815 - ESCRT III complex GO:0001778 - plasma membrane repair GO:0005643 - nuclear pore and 32 others more... GO:0005765 - lysosomal membrane GO:0005771 - multivesicular body GO:0005828 - kinetochore microtubule GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006914 - autophagy GO:0006997 - nucleus organization GO:0007080 - mitotic metaphase chromosome alignment GO:0010824 - regulation of centrosome duplication GO:0015031 - protein transport GO:0019904 - protein domain specific binding GO:0030496 - midbody GO:0031468 - nuclear membrane reassembly GO:0032509 - endosome transport via multivesicular body sorting pathway GO:0032585 - multivesicular body membrane GO:0036258 - multivesicular body assembly GO:0039702 - viral budding via host ESCRT complex GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0045324 - late endosome to vacuole transport GO:0046761 - viral budding from plasma membrane GO:0051301 - cell division GO:0051469 - vesicle fusion with vacuole GO:0061763 - multivesicular body-lysosome fusion GO:0061952 - midbody abscission GO:0070062 - extracellular exosome GO:0071985 - multivesicular body sorting pathway GO:0090148 - membrane fission GO:0097352 - autophagosome maturation GO:1901673 - regulation of mitotic spindle assembly GO:1902774 - late endosome to lysosome transport GO:1904903 - ESCRT III complex disassembly GO:1904930 - amphisome membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1	199
Hs

1	196

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Last updated: 15 Jul 2024