Interactor 1: EYA2 (O00167)
Eyes absent homolog 2 (EC 3.1.3.48)
Gene: EYA2
Interactor 2: SIX1 (Q15475)
Homeobox protein SIX1 (Sine oculis homeobox homolog 1)
Gene: SIX1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.962 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21516116, 32296183, 10906137, 23435380, unassigned1304, 20211142, 19497856 |
| Identification Methods | two hybrid, x-ray crystallography, molecular sieving, validated two hybrid, two hybrid array, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hydrolase~SIX1_SD |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
