HitPredict

Interactor 1: MICA3 (Q7RTP6)
[F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3)
Gene: MICAL3

Interactor 2: MYO19 (Q96H55)
Unconventional myosin-XIX (Myosin head domain-containing protein 1)
Gene: MYO19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2002 Hs			1 970
+	Hs
		724893 MICA3_HUMAN (1-2002): 0: 1314: 100.00		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		211643 ACTN4_HUMAN (434-1045): 2.63e-104: 359: 14.72		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		521596 ACTN1_HUMAN (434-1065): 1.24e-103: 357: 14.97		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		963391 SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		164655 SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		211515 ACTN4_HUMAN (434-1045): 2.63e-104: 359: 14.72		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		521484 ACTN1_HUMAN (434-1065): 1.24e-103: 357: 14.97		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		724781 SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		164575 SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		1068637 PLEC_HUMAN (619-1989): 3.73e-11: 71.1: 10.87		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Ce
		136791 UNC89_CAEEL (1306-1897): 2.14e-29: 131: 11.73		HUM6_CAEEL (13-923): 0: 993: 29.44
+	Hs
		724839 PLEC_HUMAN (619-1989): 3.73e-11: 71.1: 10.87		MYH9_HUMAN (9-907): 0: 997: 28.63