HitPredict

Interactor 1: K2C74 (Q7RTS7)
Keratin, type II cytoskeletal 74 (Cytokeratin-74) (CK-74) (Keratin-5c) (K5C) (Keratin-74) (K74) (Type II inner root sheath-specific keratin-K6irs4) (Type-II keratin Kb37)
Gene: KRT74

Interactor 2: RN208 (Q9H0X6)
RING finger protein 208
Gene: RNF208

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31862882
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 529 Hs			1 261
+	Hs
		380688 K2C1_HUMAN (105-471): 4.75e-164: 481: 66.21		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		729174 K22E_HUMAN (112-456): 3.26e-150: 446: 67.54		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		517786 K2C3_HUMAN (88-458): 4.88e-147: 437: 66.49		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1231034 K2C78_HUMAN (78-470): 1.81e-132: 396: 58.78		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		409229 K2C8_HUMAN (112-480): 3.62e-130: 389: 58.81		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		444555 K2C7_HUMAN (45-467): 1.88e-130: 389: 56.50		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1192466 K2C1B_HUMAN (45-471): 3.4e-110: 341: 57.27		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1205252 K2C73_HUMAN (1-456): 4.65e-105: 326: 79.43		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		318884 K2C75_HUMAN (1-465): 1.1e-95: 302: 58.49		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1110345 K2C71_HUMAN (1-456): 4.23e-91: 290: 78.99		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1062066 K2C72_HUMAN (1-529): 8.23e-87: 278: 69.00		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		531631 K2C5_HUMAN (1-456): 7.45e-82: 267: 58.68		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		380520 K2C6B_HUMAN (8-472): 3.98e-81: 265: 57.00		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		821688 K2C6C_HUMAN (8-472): 1.23e-80: 264: 57.00		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		359536 K2C6A_HUMAN (8-472): 9.42e-78: 256: 57.20		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		380572 K2C1_HUMAN (105-471): 4.75e-164: 481: 66.21		TRI23_HUMAN (116-259): 1.31e-26: 109: 22.76
+	Hs
		318781 K2C75_HUMAN (1-465): 1.1e-95: 302: 58.49		TRI23_HUMAN (116-259): 1.31e-26: 109: 22.76
+	Hs
		318903 K2C75_HUMAN (1-465): 1.1e-95: 302: 58.49		TRIM1_HUMAN (122-231): 1.51e-22: 98.3: 22.22
+	Hs
		359468 K2C6A_HUMAN (8-472): 9.42e-78: 256: 57.20		TRI23_HUMAN (116-259): 1.31e-26: 109: 22.76
+	Hs
		734597 K22O_HUMAN (1-468): 9e-70: 237: 56.95		TRI23_HUMAN (116-259): 1.31e-26: 109: 22.76