HitPredict

Interactor 1: Q7SYE2 (Q7SYE2)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: actn4

Interactor 2: MIB1 (Q804S5)
E3 ubiquitin-protein ligase mib1 (EC 2.3.2.27) (Protein mind bomb) (RING-type E3 ubiquitin transferase mib1)
Gene: MIB1

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	24714733
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank_2~EF-hand_7
Common GO terms	GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 901 Dr			1 1030
+	Dr
		1186354 Q7SYD3_DANRE (1-901): 0: 610: 77.69		MIB1_DANRE (1-1030): 0: 869: 100.00
+	Dr
		1103596 Q2YDR5_DANRE (11-901): 0: 602: 77.78		MIB1_DANRE (1-1030): 0: 869: 100.00
+	Hs
		521508 ACTN1_HUMAN (11-901): 0: 644: 86.20		DAPK1_HUMAN (419-735): 1.98e-30: 132: 29.79
+	Hs
		211541 ACTN4_HUMAN (1-901): 0: 606: 85.95		DAPK1_HUMAN (419-735): 1.98e-30: 132: 29.79
+	Hs
		164611 SPTN2_HUMAN (256-814): 1.78e-12: 73.9: 10.85		ANK3_HUMAN (639-1021): 1.43e-49: 195: 13.32
+	Hs
		963306 SPTB2_HUMAN (244-814): 2.66e-12: 73.2: 11.65		ANK3_HUMAN (639-1021): 1.43e-49: 195: 13.32
+	Hs
		1021458 SPTN4_HUMAN (253-809): 4.91e-12: 72.4: 11.94		ANK3_HUMAN (639-1021): 1.43e-49: 195: 13.32
+	Hs
		506803 SPTB1_HUMAN (210-880): 1.27e-15: 84: 12.54		ANK1_HUMAN (628-1008): 4.39e-45: 180: 13.12
+	Mm
		103603 SPTB2_MOUSE (244-814): 8.85e-13: 74.7: 11.81		ANK3_MOUSE (639-1021): 4.47e-48: 189: 13.32
+	Mm
		103598 Q3UGX2_MOUSE (230-832): 3.2e-12: 73.2: 11.22		ANK3_MOUSE (639-1021): 4.47e-48: 189: 13.32
+	Hs
		164604 SPTN2_HUMAN (256-814): 1.78e-12: 73.9: 10.85		ANK2_HUMAN (639-1021): 1.45e-47: 188: 13.27
+	Hs
		963292 SPTB2_HUMAN (244-814): 2.66e-12: 73.2: 11.65		ANK2_HUMAN (639-1021): 1.45e-47: 188: 13.27
+	Hs
		556695 SPTB2_HUMAN (244-814): 2.66e-12: 73.2: 11.65		ANK1_HUMAN (628-1008): 4.39e-45: 180: 13.12
+	Hs
		164586 SPTN2_HUMAN (256-814): 1.78e-12: 73.9: 10.85		DAPK1_HUMAN (419-735): 1.98e-30: 132: 29.79
+	Hs
		862027 SPTB2_HUMAN (244-814): 2.66e-12: 73.2: 11.65		DAPK1_HUMAN (419-735): 1.98e-30: 132: 29.79