HitPredict

Interactor 1: ACTN1 (Q7TPR4)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: HSPB2 (Q99PR8)
Heat shock protein beta-2 (HspB2)
Gene: HSPB2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26465331
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 892 Mm			1 182
+	Hs
		388189 ACTN1_HUMAN (1-892): 0: 664: 99.22		HSPB1_HUMAN (1-179): 4.68e-56: 177: 28.78
+	Hs
		211460 ACTN4_HUMAN (11-892): 0: 612: 86.51		HSPB1_HUMAN (1-179): 4.68e-56: 177: 28.78
+	Hs
		388265 ACTN2_HUMAN (11-892): 0: 607: 80.16		HSPB1_HUMAN (1-179): 4.68e-56: 177: 28.78
+	Hs
		725711 ACTN2_HUMAN (11-892): 0: 607: 80.16		HSPB8_HUMAN (6-174): 9.02e-42: 140: 26.49
+	Dm
		113825 ACTN_DROME (2-892): 0: 616: 67.07		M9NHC5_DROME (51-163): 8.62e-32: 113: 29.20
+	Hs
		388383 SPTB2_HUMAN (183-871): 8.53e-14: 78.2: 10.78		HSPB1_HUMAN (1-179): 4.68e-56: 177: 28.78
+	Mm
		1143725 SPTB2_MOUSE (243-790): 1.01e-09: 64.7: 8.53		HSPB2_MOUSE (1-182): 7.84e-54: 171: 100.00
+	Ce
		110563 H2L2C8_CAEEL (377-891): 7.37e-12: 71.2: 13.52		Q86GU1_CAEEL (6-150): 6.83e-34: 120: 26.67