HitPredict

Interactor 1: ACTN1 (Q7TPR4)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21653829
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005884 - actin filament GO:0042995 - cell projection
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 892 Mm			1 1161
+	Hs
		521588 ACTN1_HUMAN (1-892): 0: 664: 99.22		TSC1_HUMAN (1-1161): 0: 767: 86.98
+	Hs
		725682 ACTN2_HUMAN (11-892): 0: 607: 80.16		TSC1_HUMAN (1-1161): 0: 767: 86.98
+	Hs
		148339 ACTN1_HUMAN (1-892): 0: 664: 99.22		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		521484 ACTN1_HUMAN (1-892): 0: 664: 99.22		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		148171 ACTN4_HUMAN (11-892): 0: 612: 86.51		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148722 ACTN3_HUMAN (18-892): 0: 611: 78.06		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148463 ACTN2_HUMAN (11-892): 0: 607: 80.16		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		211515 ACTN4_HUMAN (11-892): 0: 612: 86.51		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Dm
		404218 ACTN_DROME (2-892): 0: 616: 67.07		MYSA_DROME (405-1117): 3.26e-20: 99.9: 10.46
+	Hs
		211632 ACTN4_HUMAN (11-892): 0: 612: 86.51		MY18A_HUMAN (367-910): 1.36e-20: 101: 9.71
+	Hs
		149277 SPTN4_HUMAN (244-867): 9.33e-20: 97.8: 10.17		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148142 SPTN2_HUMAN (224-805): 2.91e-16: 86.3: 12.84		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148690 SPTB2_HUMAN (183-871): 8.53e-14: 78.2: 10.78		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		164575 SPTN2_HUMAN (224-805): 2.91e-16: 86.3: 12.84		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		724781 SPTB2_HUMAN (183-871): 8.53e-14: 78.2: 10.78		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		148330 SPTB1_HUMAN (495-847): 3.89e-09: 62.8: 13.44		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		164647 SPTN2_HUMAN (224-805): 2.91e-16: 86.3: 12.84		MY18A_HUMAN (367-910): 1.36e-20: 101: 9.71
+	Hs
		963381 SPTB2_HUMAN (183-871): 8.53e-14: 78.2: 10.78		MY18A_HUMAN (367-910): 1.36e-20: 101: 9.71
+	Dm
		1182587 Q7KV70_DROME (363-731): 3.4e-11: 69.7: 16.40		Q9VCC9_DROME (779-1108): 3.26e-09: 63.3: 9.67