HitPredict

Interactor 1: AMPH (Q7TQF7)
Amphiphysin
Gene: AMPH

Interactor 2: DYN3 (Q8BZ98)
Dynamin-3 (EC 3.6.5.5)
Gene: Dnm3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23640057
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0048488 - synaptic vesicle endocytosis GO:0098793 - presynapse GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 686 Mm			1 863
+	Mm
		760459 AMPH_MOUSE (1-686): 7.42e-129: 398: 100.00		DYN1_MOUSE (1-841): 0: 1019: 78.99
+	Mm
		760477 AMPH_MOUSE (1-686): 7.42e-129: 398: 100.00		DYN2_MOUSE (1-863): 0: 1014: 79.04
+	Hs
		827766 AMPH_HUMAN (1-686): 2.96e-112: 355: 82.16		DYN3_HUMAN (1-863): 0: 1041: 96.33
+	Hs
		827736 AMPH_HUMAN (1-686): 2.96e-112: 355: 82.16		DYN1_HUMAN (1-846): 0: 1020: 78.65
+	Rn
		139973 AMPH_RAT (1-686): 1.11e-113: 359: 92.14		DYN1_RAT (1-846): 0: 1013: 78.41
+	Hs
		827729 AMPH_HUMAN (1-686): 2.96e-112: 355: 82.16		DYN2_HUMAN (1-863): 0: 1017: 79.04
+	Rn
		139974 AMPH_RAT (1-686): 1.11e-113: 359: 92.14		DYN2_RAT (1-863): 0: 1011: 78.93
+	Hs
		1167839 DNMBP_HUMAN (12-686): 2.62e-64: 233: 15.57		DYN3_HUMAN (1-863): 0: 1041: 96.33
+	Hs
		983387 DNMBP_HUMAN (12-686): 2.62e-64: 233: 15.57		DYN1_HUMAN (1-846): 0: 1020: 78.65
+	Hs
		840739 DNMBP_HUMAN (12-686): 2.62e-64: 233: 15.57		DYN2_HUMAN (1-863): 0: 1017: 79.04
+	Mm
		139042 BIN1_MOUSE (417-686): 1.28e-26: 116: 24.54		DYN3_MOUSE (1-863): 0: 1066: 100.00
+	Hs
		999221 EP300_HUMAN (107-613): 6.64e-31: 132: 11.92		DYN3_HUMAN (1-863): 0: 1041: 96.33
+	Hs
		840679 EP300_HUMAN (107-613): 6.64e-31: 132: 11.92		DYN2_HUMAN (1-863): 0: 1017: 79.04
+	Mm
		139028 BIN1_MOUSE (417-686): 1.28e-26: 116: 24.54		DYN1_MOUSE (1-841): 0: 1019: 78.99
+	Mm
		139029 BIN1_MOUSE (417-686): 1.28e-26: 116: 24.54		DYN2_MOUSE (1-863): 0: 1014: 79.04
+	Rn
		139987 BIN1_RAT (384-686): 4.8e-26: 115: 21.90		DYN1_RAT (1-846): 0: 1013: 78.41
+	Hs
		131222 BIN1_HUMAN (328-685): 2.46e-22: 103: 25.14		DYN2_HUMAN (1-863): 0: 1017: 79.04
+	Ce
		105220 G5ECK4_CAEEL (182-685): 2.59e-31: 133: 11.16		DYN1_CAEEL (3-787): 0: 949: 64.55
+	Sc
		599466 RV167_YEAST (11-372): 1.96e-44: 168: 17.05		VPS1_YEAST (7-658): 0: 658: 37.23
+	Hs
		231091 EP300_HUMAN (107-613): 6.64e-31: 132: 11.92		OPA1_HUMAN (7-578): 9.61e-159: 490: 19.87