HitPredict

Interactor 1: AIP (O00170)
AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein) (HBV X-associated protein 2) (XAP-2) (Immunophilin homolog ARA9)
Gene: AIP

Interactor 2: INSRR (P14616)
Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]
Gene: INSRR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FKBP_C~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 1297
+	Hs
		537736 FKBP5_HUMAN (5-330): 6.89e-57: 192: 15.20		INSRR_HUMAN (1-1297): 0: 1365: 100.00
+	Hs
		537740 FKBP8_HUMAN (6-330): 4.65e-55: 186: 17.23		INSRR_HUMAN (1-1297): 0: 1365: 100.00
+	Hs
		118695 AIP_HUMAN (1-330): 2.25e-86: 264: 100.00		EPHA8_HUMAN (454-1268): 2.42e-179: 558: 20.16
+	Hs
		118645 AIP_HUMAN (1-330): 2.25e-86: 264: 100.00		EPHB6_HUMAN (645-1291): 7.18e-161: 510: 23.91
+	Hs
		872531 FKBP5_HUMAN (5-330): 6.89e-57: 192: 15.20		EPHB4_HUMAN (455-1269): 0: 581: 21.32
+	Hs
		171301 FKBP5_HUMAN (5-330): 6.89e-57: 192: 15.20		EPHB6_HUMAN (645-1291): 7.18e-161: 510: 23.91
+	Hs
		118696 AIP_HUMAN (1-330): 2.25e-86: 264: 100.00		LTK_HUMAN (969-1291): 4.92e-73: 264: 42.17
+	Hs
		118739 AIP_HUMAN (1-330): 2.25e-86: 264: 100.00		NTRK2_HUMAN (957-1253): 1.12e-67: 247: 42.43
+	Hs
		118668 AIP_HUMAN (1-330): 2.25e-86: 264: 100.00		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91
+	Hs
		384721 PPID_HUMAN (16-329): 5.75e-64: 208: 17.21		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91
+	Hs
		169174 FKBP5_HUMAN (5-330): 6.89e-57: 192: 15.20		MUSK_HUMAN (973-1242): 8.31e-67: 245: 42.61
+	Hs
		384787 FKBP5_HUMAN (5-330): 6.89e-57: 192: 15.20		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91
+	Hs
		384676 FKBP4_HUMAN (9-330): 4.49e-55: 187: 18.89		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91
+	Hs
		384834 FKBP8_HUMAN (6-330): 4.65e-55: 186: 17.23		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91