HitPredict

Interactor 1: PIE1 (Q7X9V2)
Protein PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1 (EC 3.6.4.12) (Independent early flowering 1 protein) (Protein CHROMATIN REMODELING 13) (AtCHR13)
Gene: PIE1

Interactor 2: H2AV3 (Q9C944)
Probable histone H2A variant 3 (H2A.F/Z 3) (HTA9)
Gene: At1g52740

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	17988222, 17470967
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2055 At			1 134
+	At
		1186949 PIE1_ARATH (1-2055): 0: 1686: 100.00		H2AV2_ARATH (1-134): 1.96e-58: 179: 79.41
+	At
		188586 PIE1_ARATH (1-2055): 0: 1686: 100.00		H2AV1_ARATH (1-134): 2.63e-57: 175: 82.35
+	Hs
		1087132 INO80_HUMAN (134-1295): 0: 674: 25.61		H2A2C_HUMAN (14-133): 6.19e-54: 167: 61.16
+	Hs
		391964 INO80_HUMAN (134-1295): 0: 674: 25.61		H2A1B_HUMAN (14-133): 8.78e-54: 167: 60.33
+	Sp
		142453 SWR1_SCHPO (96-1377): 0: 676: 31.54		H2AZ_SCHPO (23-134): 4.1e-46: 147: 68.75
+	Sc
		983753 SWR1_YEAST (114-1327): 0: 686: 32.99		H2AZ_YEAST (12-134): 3.27e-40: 132: 63.42
+	Sc
		678759 RAD16_YEAST (379-1243): 1.3e-134: 443: 19.40		H2AZ_YEAST (12-134): 3.27e-40: 132: 63.42
+	Hs
		229286 SMCA5_HUMAN (976-1555): 2.75e-103: 360: 22.13		H2AZ_HUMAN (10-134): 4.79e-56: 172: 77.60
+	Hs
		229433 SMCA5_HUMAN (976-1555): 2.75e-103: 360: 22.13		H2A2B_HUMAN (14-133): 6.07e-55: 169: 60.33
+	Hs
		229279 SMCA5_HUMAN (976-1555): 2.75e-103: 360: 22.13		H2A1B_HUMAN (14-133): 8.78e-54: 167: 60.33
+	Hs
		229296 SMCA5_HUMAN (976-1555): 2.75e-103: 360: 22.13		H2AX_HUMAN (14-132): 5.11e-54: 167: 61.67
+	Hs
		470170 CHD8_HUMAN (836-1613): 3.39e-96: 350: 15.71		H2AZ_HUMAN (10-134): 4.79e-56: 172: 77.60
+	Hs
		469951 SMCA1_HUMAN (881-1536): 2.14e-99: 348: 21.08		H2AZ_HUMAN (10-134): 4.79e-56: 172: 77.60
+	Hs
		391915 CHD8_HUMAN (836-1613): 3.39e-96: 350: 15.71		H2A1B_HUMAN (14-133): 8.78e-54: 167: 60.33
+	Hs
		555654 CHD8_HUMAN (836-1613): 3.39e-96: 350: 15.71		H2AX_HUMAN (14-132): 5.11e-54: 167: 61.67
+	Hs
		555306 SMCA1_HUMAN (881-1536): 2.14e-99: 348: 21.08		H2AX_HUMAN (14-132): 5.11e-54: 167: 61.67
+	Hs
		469971 SMCA4_HUMAN (988-1587): 1.73e-94: 342: 18.64		H2AZ_HUMAN (10-134): 4.79e-56: 172: 77.60
+	Hs
		555359 SMCA4_HUMAN (988-1587): 1.73e-94: 342: 18.64		H2AX_HUMAN (14-132): 5.11e-54: 167: 61.67
+	Hs
		555358 SMCA2_HUMAN (988-1611): 1.77e-93: 338: 17.92		H2AX_HUMAN (14-132): 5.11e-54: 167: 61.67
+	Hs
		470278 SMCA1_HUMAN (881-1536): 2.14e-99: 348: 21.08		H2A1_HUMAN (1-133): 5.74e-34: 116: 58.96