HitPredict

Interactor 1: Q7YSQ1 (Q7YSQ1)
Notch
Gene: N

Interactor 2: Q9VCM6 (Q9VCM6)
IP14385p
Gene: DmelCG4393

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	15710747
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank~Ank_4, Ank_2~Ank_2, Ank_2~Ank_4
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 527 Dm			1 1325
+	Dm
		422847 NOTCH_DROME (1-527): 9.93e-119: 387: 100.00		Q9VCM6_DROME (1-1325): 0: 733: 100.00
+	Mm
		970499 ANK1_MOUSE (160-525): 1.17e-87: 297: 18.99		ANS1B_MOUSE (1-1304): 4.91e-117: 398: 21.42
+	Dm
		422915 NOTCH_DROME (1-527): 9.93e-119: 387: 100.00		MIB_DROME (5-293): 2.48e-68: 254: 26.06
+	Dm
		1187207 Q7YSQ1_DROME (1-527): 1.27e-113: 348: 100.00		Q8SWY2_DROME (6-1030): 8.21e-69: 254: 13.23
+	Dm
		1187219 Q7YSQ1_DROME (1-527): 1.27e-113: 348: 100.00		MIB_DROME (5-293): 2.48e-68: 254: 26.06
+	Hs
		299128 TNKS2_HUMAN (128-526): 4.76e-85: 287: 20.00		SASH1_HUMAN (518-1065): 1.09e-78: 286: 16.78
+	Hs
		166919 ANK3_HUMAN (39-527): 1.26e-119: 390: 18.15		ANR28_HUMAN (170-404): 1.05e-23: 111: 16.26
+	Hs
		1021462 ANK3_HUMAN (39-527): 1.26e-119: 390: 18.15		Q9H4D1_HUMAN (5-137): 3.08e-18: 92.9: 28.57
+	Hs
		883496 ANK3_HUMAN (39-527): 1.26e-119: 390: 18.15		RIPK4_HUMAN (5-137): 3.05e-18: 92.9: 28.57
+	Dm
		65546 NOTCH_DROME (1-527): 9.93e-119: 387: 100.00		A8JNM5_DROME (36-256): 1.22e-09: 65.5: 27.48
+	Hs
		167042 NOTC3_HUMAN (1-520): 1.8e-102: 340: 43.48		ANR28_HUMAN (170-404): 1.05e-23: 111: 16.26
+	Hs
		1237561 NOTC3_HUMAN (1-520): 1.8e-102: 340: 43.48		ANR44_HUMAN (166-392): 3.78e-23: 109: 15.79
+	Hs
		804293 NOTC1_HUMAN (23-504): 2.64e-91: 308: 40.48		ANR44_HUMAN (166-392): 3.78e-23: 109: 15.79
+	Hs
		166869 TNKS1_HUMAN (125-527): 7.07e-87: 293: 20.09		ANR28_HUMAN (170-404): 1.05e-23: 111: 16.26
+	Hs
		862012 DAPK1_HUMAN (53-384): 1.38e-82: 282: 24.29		DAPK1_HUMAN (3-157): 8.75e-27: 121: 24.00
+	Hs
		167014 TNKS2_HUMAN (128-526): 4.76e-85: 287: 20.00		ANR28_HUMAN (170-404): 1.05e-23: 111: 16.26
+	Mm
		1193396 DAPK1_MOUSE (53-384): 1.23e-82: 282: 24.29		MIB1_MOUSE (89-330): 1.1e-24: 114: 18.85
+	Hs
		862070 DAPK1_HUMAN (53-384): 1.38e-82: 282: 24.29		MIB1_HUMAN (89-330): 1.1e-24: 114: 18.85
+	Hs
		310030 TNKS1_HUMAN (125-527): 7.07e-87: 293: 20.09		TNKS1_HUMAN (2-109): 1.83e-15: 84.3: 24.03
+	Hs
		1329533 TNKS2_HUMAN (128-526): 4.76e-85: 287: 20.00		TNKS2_HUMAN (2-86): 1.04e-15: 85: 25.88