Interactor 1: ZCCHV (Q7Z2W4)
Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Inactive Poly [ADP-ribose] polymerase 13) (PARP13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP)
Gene: ZC3HAV1

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 32877691
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0032481 - positive regulation of type I interferon production
GO:0032727 - positive regulation of interferon-alpha production
GO:0032728 - positive regulation of interferon-beta production
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045071 - negative regulation of viral genome replication
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024