HitPredict

Interactor 1: ZCCHV (Q7Z2W4)
Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Inactive Poly [ADP-ribose] polymerase 13) (PARP13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP)
Gene: ZC3HAV1

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30209976, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0046872 - metal ion binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 902 Hs			1 1191
+	Hs
		1136145 ZCCHV_HUMAN (1-902): 0: 1277: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		257639 ZCCHV_HUMAN (1-902): 0: 1277: 100.00		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		455536 PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1188580 PARPT_HUMAN (273-895): 0: 578: 23.82		KMT2C_HUMAN (351-895): 4.49e-14: 79.7: 9.35
+	Hs
		1188971 PARPT_HUMAN (273-895): 0: 578: 23.82		CHD7_HUMAN (491-1004): 4.82e-13: 76.2: 7.21
+	Hs
		257640 PARPT_HUMAN (273-895): 0: 578: 23.82		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		1056877 PARPT_HUMAN (273-895): 0: 578: 23.82		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Hs
		1170061 PARPT_HUMAN (273-895): 0: 578: 23.82		SRCAP_HUMAN (482-817): 8.67e-10: 65.7: 15.61
+	Hs
		1188652 PARPT_HUMAN (273-895): 0: 578: 23.82		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Hs
		455957 PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20		CHD7_HUMAN (491-1004): 4.82e-13: 76.2: 7.21
+	Hs
		455579 PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20		SRCAP_HUMAN (482-817): 8.67e-10: 65.7: 15.61
+	Hs
		455255 PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20		SC24C_HUMAN (362-642): 1.58e-09: 64.6: 12.98
+	Hs
		455721 PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Hs
		455836 PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20		CECR2_HUMAN (356-1006): 5.51e-09: 62.7: 8.82
+	Hs
		1056981 TNKS2_HUMAN (722-894): 1.37e-45: 180: 21.60		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Hs
		310053 TNKS1_HUMAN (725-894): 8.22e-44: 174: 20.95		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21