Interactor 1: TICRR (Q7Z2Z1)
Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)
Gene: TICRR

Interactor 2: TOPB1 (Q92547)
DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)
Gene: TOPBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.735

The method score is based on:

Property Details
Experiments 23696651, 28439015, 23704573, 30295604, 30695077, 21700459
Identification Methods affinity chromatography technology, pull down, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
GO:0007095 - mitotic G2 DNA damage checkpoint signaling
GO:0010212 - response to ionizing radiation
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1910
Hs

1 1522
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024