Interactor 1: SETX (Q7Z333)
Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein) (SEN1 homolog) (Senataxin)
Gene: SETX

Interactor 2: SETX (Q7Z333)
Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein) (SEN1 homolog) (Senataxin)
Gene: SETX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 24244371
Identification Methods two hybrid, molecular sieving, cross-linking study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_11~AAA_11, AAA_11~AAA_12, AAA_12~AAA_12
Common GO terms GO:0000165 - MAPK cascade
GO:0000228 - nuclear chromosome
GO:0000781 - chromosome, telomeric region
GO:0001147 - transcription termination site sequence-specific DNA binding
GO:0003677 - DNA binding
and 36 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 2677
Hs

1 2677
+ Hs
+ Sc
+ Dm
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024