HitPredict

Interactor 1: NUP54 (Q7Z3B4)
Nucleoporin p54 (54 kDa nucleoporin)
Gene: NUP54

Interactor 2: RN166 (Q96A37)
E3 ubiquitin-protein ligase RNF166 (EC 2.3.2.27) (RING finger protein 166) (RING-type E3 ubiquitin transferase RNF166)
Gene: RNF166

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 507 Hs			1 237
+	Hs
		858028 NUP98_HUMAN (2-257): 4.92e-12: 70.8: 15.44		RN166_HUMAN (1-237): 6.66e-64: 200: 100.00
+	Hs
		1024736 P121A_HUMAN (2-189): 1.69e-09: 62.7: 18.78		TRAF3_HUMAN (15-215): 4.28e-31: 121: 20.29
+	Hs
		727325 NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04		KCMF1_HUMAN (143-213): 4.51e-21: 92.2: 33.80
+	Mm
		761821 NUP98_MOUSE (2-257): 2.9e-11: 68.5: 16.60		TRAF2_MOUSE (15-186): 2.58e-25: 104: 20.11
+	Hs
		1020863 P121A_HUMAN (2-189): 1.69e-09: 62.7: 18.78		TRAF2_HUMAN (15-186): 9.47e-27: 109: 20.65