Interactor 1: NUP54 (Q7Z3B4)
Nucleoporin p54 (54 kDa nucleoporin)
Gene: NUP54

Interactor 2: NUP58 (Q9BVL2)
Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1)
Gene: NUP58

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 25416956, 26496610, 28514442, 32296183, 30021884, 33961781, 37071682, 31515488, unassigned1304, 32814053
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Nucleoporin_FG2~Nup54, Nucleoporin_FG2~Nup54_C
Common GO terms GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0006913 - nucleocytoplasmic transport
GO:0017056 - structural constituent of nuclear pore
GO:0031965 - nuclear membrane
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 507
Hs

1 599
+ Rn
+ Xl
+ Xl
+ Hs
+ Tt
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Ce
+ Sc
+ Tt
+ Hs
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024