HitPredict

Interactor 1: NUP54 (Q7Z3B4)
Nucleoporin p54 (54 kDa nucleoporin)
Gene: NUP54

Interactor 2: N62CL (Q9H1M0)
Nucleoporin-62 C-terminal-like protein
Gene: NUP62CL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.858

Property	Details
Experiments	28514442, 33961781, 31515488
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Nsp1_C~Nup54
Common GO terms	GO:0017056 - structural constituent of nuclear pore GO:0044613 - nuclear pore central transport channel
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 507 Hs			1 184
+	Hs
		740188 NUP54_HUMAN (1-507): 1.14e-157: 459: 100.00		NUP62_HUMAN (3-173): 4.99e-49: 167: 46.64
+	Rn
		572718 NUP54_RAT (1-507): 1.28e-156: 457: 95.29		NUP62_RAT (41-173): 2.76e-46: 160: 60.15
+	Xl
		1160706 Q6PAY1_XENLA (1-507): 1.37e-148: 436: 74.07		Q91349_XENLA (4-173): 7.51e-52: 175: 53.07
+	Xl
		111951 K9ZTJ6_XENLA (1-507): 5.92e-143: 423: 71.46		Q91349_XENLA (4-173): 7.51e-52: 175: 53.07
+	Sp
		194964 NUP44_SCHPO (60-493): 2.71e-79: 255: 18.16		NSP1_SCHPO (4-163): 2.95e-39: 142: 24.69
+	Tt
		101860 NUP57_CHATD (181-496): 1.2e-85: 268: 18.71		NSP1_CHATD (53-160): 2.36e-25: 103: 25.00
+	Sc
		541897 NU145_YEAST (2-422): 1.95e-69: 243: 15.68		NSP1_YEAST (8-159): 1.46e-31: 121: 22.37
+	Sc
		541895 NUP57_YEAST (3-489): 1.88e-59: 206: 18.52		NSP1_YEAST (8-159): 1.46e-31: 121: 22.37
+	Hs
		727210 NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04		NUP62_HUMAN (3-173): 4.99e-49: 167: 46.64
+	Xl
		1265022 Q9PVZ2_XENLA (3-305): 4.65e-09: 61.2: 15.14		Q91349_XENLA (4-173): 7.51e-52: 175: 53.07
+	Tt
		101910 NU159_CHATD (3-212): 6.04e-24: 108: 14.35		NSP1_CHATD (53-160): 2.36e-25: 103: 25.00
+	Sc
		541912 NU116_YEAST (5-265): 1.36e-12: 72.3: 13.51		NSP1_YEAST (8-159): 1.46e-31: 121: 22.37
+	Sc
		541908 NUP49_YEAST (6-267): 5.59e-11: 66.6: 11.28		NSP1_YEAST (8-159): 1.46e-31: 121: 22.37
+	Sc
		541888 NU159_YEAST (44-283): 8.5e-10: 63.5: 10.36		NSP1_YEAST (8-159): 1.46e-31: 121: 22.37
+	Dm
		1177911 NUP54_DROME (20-265): 7.39e-09: 60.4: 11.74		NUP62_DROME (37-157): 2.56e-32: 121: 43.55
+	Tt
		101884 NUP49_CHATD (5-208): 5e-12: 70: 16.09		NSP1_CHATD (53-160): 2.36e-25: 103: 25.00