HitPredict

Interactor 1: PARPT (Q7Z3E1)
Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7) (TCDD-inducible poly [ADP-ribose] polymerase)
Gene: TIPARP

Interactor 2: MED15 (Q96RN5)
Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein)
Gene: MED15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35439318
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 657 Hs			1 788
+	Hs
		1188553 PARPT_HUMAN (1-657): 0: 1089: 100.00		MINK1_HUMAN (173-542): 1.75e-26: 118: 18.18
+	Hs
		1189131 PARPT_HUMAN (1-657): 0: 1089: 100.00		CABIN_HUMAN (72-522): 6.45e-26: 117: 11.50
+	Hs
		1188727 PARPT_HUMAN (1-657): 0: 1089: 100.00		EP400_HUMAN (236-579): 1.3e-19: 97: 20.00
+	Hs
		1188632 PARPT_HUMAN (1-657): 0: 1089: 100.00		TITIN_HUMAN (156-460): 5.01e-12: 72.4: 11.53
+	Hs
		1188652 PARPT_HUMAN (1-657): 0: 1089: 100.00		CBP_HUMAN (139-583): 4.11e-10: 65.9: 11.24
+	Hs
		1188971 PARPT_HUMAN (1-657): 0: 1089: 100.00		CHD7_HUMAN (63-279): 3.68e-09: 62.8: 15.07
+	Hs
		131728 PARPT_HUMAN (1-657): 0: 1089: 100.00		BCL9_HUMAN (76-549): 7.24e-09: 61.7: 11.02