HitPredict

Interactor 1: MIER3 (Q7Z3K6)
Mesoderm induction early response protein 3 (Mi-er3)
Gene: MIER3

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 127
+	Hs
		918473 MIER3_HUMAN (1-550): 1.73e-165: 483: 100.00		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1189325 MIER3_HUMAN (1-550): 1.73e-165: 483: 100.00		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Hs
		883039 MIER1_HUMAN (1-511): 1.94e-106: 330: 43.64		H2BFS_HUMAN (1-127): 8.37e-54: 166: 82.68
+	Hs
		918513 MIER1_HUMAN (1-511): 1.94e-106: 330: 43.64		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1229948 MIER1_HUMAN (1-511): 1.94e-106: 330: 43.64		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00
+	Hs
		1229940 MIER1_HUMAN (1-511): 1.94e-106: 330: 43.64		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Hs
		1031872 MTA1_HUMAN (102-511): 9.79e-99: 316: 16.63		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		296039 MTA2_HUMAN (78-493): 5.53e-94: 302: 16.21		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		295947 MTA2_HUMAN (78-493): 5.53e-94: 302: 16.21		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		1087471 RCOR1_HUMAN (142-524): 1.87e-71: 238: 17.22		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		918766 RCOR1_HUMAN (142-524): 1.87e-71: 238: 17.22		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1087204 MDEAS_HUMAN (65-497): 3.5e-59: 214: 15.77		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		918453 MDEAS_HUMAN (65-497): 3.5e-59: 214: 15.77		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04