HitPredict

Interactor 1: K1C27 (Q7Z3Y8)
Keratin, type I cytoskeletal 27 (Cytokeratin-27) (CK-27) (Keratin-25C) (K25C) (Keratin-27) (K27) (Type I inner root sheath-specific keratin-K25irs3)
Gene: KRT27

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 459 Hs			1 1193
+	Hs
		444459 K1C19_HUMAN (78-396): 9.88e-114: 342: 57.68		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		318869 K2C75_HUMAN (2-411): 1.16e-87: 279: 23.71		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		280909 KRT37_HUMAN (14-409): 9.44e-73: 238: 35.61		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		281044 KRT38_HUMAN (32-412): 5.99e-73: 238: 37.01		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		551676 K1C17_HUMAN (36-440): 5.27e-147: 427: 52.91		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		359355 K1C14_HUMAN (61-446): 5.6e-148: 432: 54.26		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		725143 K1C17_HUMAN (36-440): 5.27e-147: 427: 52.91		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		724787 K1C17_HUMAN (36-440): 5.27e-147: 427: 52.91		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		49550 A1A4E9_HUMAN (72-397): 3.26e-118: 355: 59.20		MYH1_HUMAN (287-962): 1.25e-30: 133: 11.18
+	Hs
		522534 K1C13_HUMAN (72-397): 2.2e-118: 355: 59.51		MYH1_HUMAN (287-962): 1.25e-30: 133: 11.18
+	Hs
		359462 K2C6A_HUMAN (55-419): 2.56e-115: 351: 20.70		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		444307 K1C19_HUMAN (78-396): 9.88e-114: 342: 57.68		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		445052 K1C16_HUMAN (80-406): 1.63e-119: 359: 60.55		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		444372 K1C19_HUMAN (78-396): 9.88e-114: 342: 57.68		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		531529 K2C5_HUMAN (55-402): 6.57e-73: 242: 22.54		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		280880 KRT37_HUMAN (14-409): 9.44e-73: 238: 35.61		EEA1_HUMAN (691-1193): 8.44e-18: 91.8: 12.35
+	Hs
		280983 KRT38_HUMAN (32-412): 5.99e-73: 238: 37.01		EEA1_HUMAN (691-1193): 8.44e-18: 91.8: 12.35
+	Hs
		821662 K2C6C_HUMAN (55-418): 2.74e-73: 242: 20.49		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40