HitPredict

Interactor 1: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Interactor 2: NUP43 (Q8NFH3)
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)
Gene: NUP43

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	26912792
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 540 Hs			1 380
+	Hs
		903335 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24
+	Hs
		1192155 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30
+	Hs
		1056899 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80
+	Hs
		1244430 CHAP1_HUMAN (196-539): 2.7e-10: 65.2: 10.38		NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80
+	Hs
		1170071 SRCAP_HUMAN (88-342): 3.17e-09: 62.1: 16.86		NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80
+	Hs
		1192190 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		GRWD1_HUMAN (68-330): 6.16e-56: 191: 15.84
+	Hs
		1281391 PRR36_HUMAN (93-535): 5.51e-09: 61.4: 10.13		FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30
+	Hs
		903450 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24
+	Hs
		903374 KMT2C_HUMAN (57-528): 6.72e-09: 61: 10.42		WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24
+	Mm
		903669 KMT2C_MOUSE (128-523): 8.47e-09: 60.6: 10.33		WDR5_MOUSE (3-289): 4.3e-58: 193: 14.24
+	Hs
		997784 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59
+	Hs
		1083295 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		RBBP7_HUMAN (216-378): 1.89e-18: 88.3: 14.13
+	Ce
		557846 RPB1_CAEEL (140-503): 1.25e-15: 82.6: 14.02		LIN53_CAEEL (216-378): 1.44e-20: 94.1: 14.29
+	Hs
		1056932 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04
+	Hs
		1056974 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		WDR33_HUMAN (173-376): 7.97e-20: 93.6: 16.51
+	Hs
		997857 CHAP1_HUMAN (196-539): 2.7e-10: 65.2: 10.38		RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59
+	Hs
		997865 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59
+	Hs
		1083355 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		RBBP7_HUMAN (216-378): 1.89e-18: 88.3: 14.13