HitPredict

Interactor 1: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0007165 - signal transduction GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051091 - positive regulation of DNA-binding transcription factor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 540 Hs			1 530
+	Hs
		1192145 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1186078 MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		554348 MUC1_HUMAN (160-534): 7.43e-16: 83.3: 10.90		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269843 YM012_HUMAN (41-457): 2.29e-15: 81: 12.17		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		867111 SC24C_HUMAN (116-429): 9.64e-11: 66.7: 15.43		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1056909 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269367 CHAP1_HUMAN (196-539): 2.7e-10: 65.2: 10.38		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369911 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368927 MUC1_HUMAN (160-534): 7.43e-16: 83.3: 10.90		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369607 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370251 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		101423 F8VPR5_MOUSE (82-395): 1.45e-11: 69.8: 14.24		ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72
+	Mm
		101427 F8VPR5_MOUSE (82-395): 1.45e-11: 69.8: 14.24		RXRG_MOUSE (13-499): 5.3e-117: 355: 22.56
+	Hs
		510035 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		ERR1_HUMAN (85-497): 1.88e-112: 342: 35.65
+	Hs
		377615 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		490111 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		COT1_HUMAN (83-502): 2.36e-106: 326: 23.88
+	Hs
		487557 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487431 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487681 CHAP1_HUMAN (196-539): 2.7e-10: 65.2: 10.38		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487695 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59