HitPredict

Interactor 1: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Interactor 2: UBP28 (Q96RU2)
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
Gene: USP28

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30410068
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 540 Hs			1 1077
+	Hs
		1190123 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		UBP25_HUMAN (1-1068): 0: 977: 48.38
+	Hs
		1056946 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		UBP28_HUMAN (1-1077): 0: 1069: 100.00
+	Hs
		259293 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		UBP12_HUMAN (157-475): 5.94e-65: 226: 17.10
+	Hs
		905389 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		UBP46_HUMAN (158-406): 1.63e-64: 224: 20.36
+	Hs
		1273585 MYO15_HUMAN (94-518): 2.79e-17: 87.9: 13.82		UBP13_HUMAN (28-649): 3.31e-72: 259: 12.85
+	Hs
		1192153 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		USP9X_HUMAN (136-452): 1.14e-61: 233: 18.33
+	Mm
		88455 D3Z656_MOUSE (196-539): 1.13e-11: 69.8: 11.86		UBP48_MOUSE (145-399): 4.73e-71: 259: 26.52
+	Hs
		271127 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		UBP2_HUMAN (434-653): 1.59e-15: 83.1: 17.86
+	Hs
		1056916 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		UBP13_HUMAN (28-649): 3.31e-72: 259: 12.85
+	Hs
		1190128 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		UBP22_HUMAN (428-654): 3.12e-11: 69.2: 18.42
+	Dm
		1366516 Q9VGW4_DROME (226-513): 2.75e-09: 62.1: 14.29		UBP36_DROME (1-544): 1.84e-68: 251: 14.97
+	Hs
		1056938 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		UBP47_HUMAN (156-403): 7.25e-49: 191: 19.85
+	Hs
		1192154 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13
+	Mm
		1149452 HUWE1_MOUSE (108-539): 1.87e-18: 91.8: 13.89		UBP7_MOUSE (547-839): 6.59e-23: 108: 18.91
+	Hs
		1273897 MAGE1_HUMAN (183-537): 6.13e-11: 67.2: 9.58		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13
+	Hs
		1056917 MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13
+	Hs
		1273811 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13