HitPredict

Interactor 1: TT21B (Q7Z4L5)
Tetratricopeptide repeat protein 21B (TPR repeat protein 21B) (Intraflagellar transport 139 homolog)
Gene: TTC21B

Interactor 2: WDR19 (Q8NEZ3)
WD repeat-containing protein 19 (Intraflagellar transport 144 homolog)
Gene: WDR19

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	27173435, 27932497
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton GO:0005929 - cilium GO:0030991 - intraciliary transport particle A GO:0035721 - intraciliary retrograde transport and 2 others more... GO:0060271 - cilium assembly GO:0097542 - ciliary tip
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1316 Hs			1 1342
+	Hs
		1242712 TT21A_HUMAN (2-1316): 0: 848: 51.10		IF140_HUMAN (18-1248): 2.07e-137: 459: 14.62
+	Hs
		1190473 TT21B_HUMAN (1-1316): 0: 846: 100.00		IF140_HUMAN (18-1248): 2.07e-137: 459: 14.62
+	Hs
		1190477 TT21B_HUMAN (1-1316): 0: 846: 100.00		WDR35_HUMAN (102-1321): 1.01e-69: 258: 11.43
+	Hs
		1190475 TT21B_HUMAN (1-1316): 0: 846: 100.00		IF122_HUMAN (233-1202): 1.93e-61: 233: 12.19
+	Ce
		953726 TTC21_CAEEL (8-1315): 0: 607: 29.93		P90757_CAEEL (20-1254): 3.13e-99: 350: 11.87
+	Hs
		174768 OGT1_HUMAN (11-423): 9.34e-28: 123: 11.91		WDR5_HUMAN (16-168): 3.73e-22: 101: 19.75
+	Hs
		300095 PRP6_HUMAN (827-1315): 4.26e-23: 108: 11.87		WDR5_HUMAN (16-168): 3.73e-22: 101: 19.75
+	Hs
		1160993 CTR9_HUMAN (826-1314): 5.19e-33: 141: 13.70		FZR1_HUMAN (197-386): 2.05e-10: 66.8: 11.98
+	Hs
		1024279 IFT88_HUMAN (864-1316): 3.63e-25: 115: 12.55		IF172_HUMAN (585-1113): 1.32e-17: 91.4: 10.74
+	Rn
		1118803 CDC27_RAT (747-1067): 4.77e-16: 85.6: 14.99		CDC20_RAT (4-251): 6.16e-24: 109: 17.31
+	Mm
		1142546 IFT88_MOUSE (864-1314): 9.01e-29: 127: 11.63		IFT80_MOUSE (22-209): 1.83e-10: 67.6: 15.74
+	Hs
		1024278 IFT88_HUMAN (864-1316): 3.63e-25: 115: 12.55		IFT80_HUMAN (22-209): 5.64e-11: 69.1: 15.23
+	At
		1225852 CDC23_ARATH (727-1123): 3.31e-13: 76: 10.54		FZR2_ARATH (17-274): 1.46e-21: 101: 15.47
+	Hs
		300287 PRP6_HUMAN (827-1315): 4.26e-23: 108: 11.87		FZR1_HUMAN (197-386): 2.05e-10: 66.8: 11.98
+	Mm
		56871 CDC27_MOUSE (781-1067): 4.02e-16: 86: 12.21		FZR1_MOUSE (197-386): 1.92e-10: 66.8: 11.98
+	Mm
		56870 CDC27_MOUSE (781-1067): 4.02e-16: 86: 12.21		CDC20_MOUSE (24-164): 9.36e-10: 64.7: 23.13
+	Dm
		1337225 Q9I7L8_DROME (673-1012): 2.3e-13: 76.8: 15.16		Q9W4H9_DROME (197-370): 7.19e-12: 71.4: 14.29
+	Sp
		293623 APC8_SCHPO (441-706): 1.78e-13: 76.9: 13.33		SLP1_SCHPO (60-162): 1.13e-11: 70.9: 26.92
+	Sc
		561125 CDC23_YEAST (509-1015): 1.93e-13: 77.2: 12.85		CDH1_YEAST (60-162): 1.77e-11: 70.5: 35.92
+	At
		1228254 CDC23_ARATH (727-1123): 3.31e-13: 76: 10.54		FZR3_ARATH (4-134): 7.45e-12: 71.4: 19.85