HitPredict

Interactor 1: TT21B (Q7Z4L5)
Tetratricopeptide repeat protein 21B (TPR repeat protein 21B) (Intraflagellar transport 139 homolog)
Gene: TTC21B

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21182203
Identification Methods	cosedimentation through density gradient
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1316 Hs			1 530
+	Hs
		1160955 CTR9_HUMAN (826-1314): 5.19e-33: 141: 13.70		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		175077 OGT1_HUMAN (11-423): 9.34e-28: 123: 11.91		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369839 CTR9_HUMAN (826-1314): 5.19e-33: 141: 13.70		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1161403 SKI3_HUMAN (848-1310): 3.05e-17: 90.1: 11.51		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		174531 OGT1_HUMAN (11-423): 9.34e-28: 123: 11.91		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1269881 CDC23_HUMAN (762-1015): 1.59e-11: 70.6: 10.55		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		300025 PRP6_HUMAN (827-1315): 4.26e-23: 108: 11.87		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369840 SKI3_HUMAN (848-1310): 3.05e-17: 90.1: 11.51		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369072 STIP1_HUMAN (95-435): 5.85e-09: 62.3: 14.45		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		1142644 CTR9_MOUSE (826-1314): 1.05e-32: 140: 13.70		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Mm
		1142687 OGT1_MOUSE (11-423): 1.31e-27: 123: 11.91		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Mm
		56867 CDC27_MOUSE (781-1067): 4.02e-16: 86: 12.21		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Hs
		377572 TTC28_HUMAN (10-438): 5.95e-13: 76.2: 13.41		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377132 STIP1_HUMAN (95-435): 5.85e-09: 62.3: 14.45		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487530 CTR9_HUMAN (826-1314): 5.19e-33: 141: 13.70		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		174572 OGT1_HUMAN (11-423): 9.34e-28: 123: 11.91		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		300039 PRP6_HUMAN (827-1315): 4.26e-23: 108: 11.87		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		414449 STIP1_HUMAN (95-435): 5.85e-09: 62.3: 14.45		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		487173 STIP1_HUMAN (95-435): 5.85e-09: 62.3: 14.45		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59