HitPredict

Interactor 1: HDGR2 (Q7Z4V5)
Hepatoma-derived growth factor-related protein 2 (HDGF-related protein 2) (HRP-2) (Hepatoma-derived growth factor 2) (HDGF-2)
Gene: HDGFL2

Interactor 2: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36373674
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 671 Hs			1 1101
+	Hs
		1221647 NSD1_HUMAN (2-668): 2.86e-90: 310: 12.29		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		331844 NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221713 NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		266035 PSIP1_HUMAN (1-553): 1.35e-54: 197: 23.49		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221830 ZMYD8_HUMAN (6-605): 7.73e-40: 159: 14.24		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221867 HDGR3_HUMAN (2-194): 5.06e-22: 96.6: 43.43		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1154049 NIPBL_HUMAN (100-662): 1.42e-17: 89.7: 16.10		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		850999 HDGF_HUMAN (3-234): 8.81e-26: 108: 35.78		SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91
+	Hs
		1154087 NIPBL_HUMAN (100-662): 1.42e-17: 89.7: 16.10		SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91
+	Mm
		1154102 NIPBL_MOUSE (63-670): 3.24e-16: 85.5: 15.01		SMC3_MOUSE (51-1061): 1.42e-81: 292: 13.91
+	Xl
		292738 PD5BA_XENLA (40-408): 6.51e-10: 64.7: 17.52		SMC3_XENLA (51-1090): 4.8e-50: 195: 11.68
+	Xl
		1115499 PD5BA_XENLA (40-408): 6.51e-10: 64.7: 17.52		Q8AW91_XENLA (51-1090): 1.89e-49: 193: 11.61