HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 18263896
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0010628 - positive regulation of gene expression GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 2477
+	Hs
		121070 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		FINC_HUMAN (1-2477): 0: 1538: 100.00
+	Hs
		362790 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		FINC_HUMAN (1-2477): 0: 1538: 100.00
+	Hs
		362931 LEG7_HUMAN (224-354): 6.94e-39: 136: 37.04		FINC_HUMAN (1-2477): 0: 1538: 100.00
+	Hs
		362725 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		FINC_HUMAN (1-2477): 0: 1538: 100.00
+	Hs
		572370 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		SDK2_HUMAN (1428-2469): 8.32e-95: 345: 10.88
+	Hs
		814965 LEG7_HUMAN (224-354): 6.94e-39: 136: 37.04		SDK2_HUMAN (1428-2469): 8.32e-95: 345: 10.88
+	Hs
		449281 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		SDK2_HUMAN (1428-2469): 8.32e-95: 345: 10.88
+	Hs
		121183 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		SDK1_HUMAN (1720-2405): 2.22e-31: 137: 8.25
+	Hs
		121099 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31
+	Hs
		449191 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		PTPRB_HUMAN (574-1553): 1.99e-62: 239: 15.64
+	Hs
		572394 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		SDK1_HUMAN (1720-2405): 2.22e-31: 137: 8.25
+	Hs
		814978 LEG7_HUMAN (224-354): 6.94e-39: 136: 37.04		SDK1_HUMAN (1720-2405): 2.22e-31: 137: 8.25
+	Hs
		449306 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		SDK1_HUMAN (1720-2405): 2.22e-31: 137: 8.25
+	Hs
		439224 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56
+	Hs
		540411 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31
+	Hs
		449192 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		PTPRD_HUMAN (1998-2416): 1.38e-17: 92.5: 9.47
+	Hs
		1253493 PPL13_HUMAN (221-353): 1.32e-31: 117: 25.00		TENR_HUMAN (207-352): 4.02e-10: 67.6: 14.97
+	Hs
		50511 PPL13_HUMAN (221-353): 1.32e-31: 117: 25.00		A1L306_HUMAN (207-352): 6.04e-10: 67.2: 14.97