HitPredict

Interactor 1: GP141 (Q7Z602)
Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13)
Gene: GPR141

Interactor 2: TTYH3 (Q9C0H2)
Protein tweety homolog 3 (hTTY3) (Volume-regulated anion channel subunit TTYH3)
Gene: TTYH3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 523
+	Hs
		1031074 GPR17_HUMAN (6-303): 3.69e-66: 213: 19.08		TTYH3_HUMAN (1-523): 0: 764: 100.00
+	Hs
		782469 P2RY2_HUMAN (13-289): 9.34e-66: 212: 20.07		TTYH3_HUMAN (1-523): 0: 764: 100.00
+	Hs
		666347 NK3R_HUMAN (2-301): 9.16e-64: 209: 12.01		TTYH3_HUMAN (1-523): 0: 764: 100.00
+	Hs
		1319358 P2Y12_HUMAN (5-301): 5.62e-49: 167: 19.74		TTYH3_HUMAN (1-523): 0: 764: 100.00
+	Hs
		1040088 MTR1L_HUMAN (10-303): 1.92e-61: 207: 11.37		TTYH1_HUMAN (6-416): 9.68e-165: 476: 39.37