Interactor 1: SPRE1 (Q7Z699)
Sprouty-related, EVH1 domain-containing protein 1 (Spred-1) (hSpred1)
Gene: SPRED1
Interactor 2: TRIB3 (Q96RU7)
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (SINK) (p65-interacting inhibitor of NF-kappa-B)
Gene: TRIB3
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.60 | 0.534 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32814053 |
| Identification Methods | validated two hybrid, two hybrid array, two hybrid pooling approach, luminescence based mammalian interactome mapping |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006469 - negative regulation of protein kinase activity GO:0019901 - protein kinase binding |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
