HitPredict

Interactor 1: RBBP6 (Q7Z6E9)
E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)
Gene: RBBP6

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1792 Hs			1 530
+	Hs
		369909 RBBP6_HUMAN (1-1792): 1.97e-152: 516: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1056909 MDC1_HUMAN (508-1516): 4.61e-24: 113: 10.37		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		517813 NFH_HUMAN (1119-1712): 3.93e-22: 106: 11.20		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1244235 BD1L1_HUMAN (851-1782): 4.77e-20: 100: 13.46		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269667 MUC5B_HUMAN (63-1573): 2.71e-18: 94.6: 8.06		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1243831 KMT2C_HUMAN (88-1775): 2.2e-16: 88.1: 7.78		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1264560 ELYS_HUMAN (577-1779): 2.2e-15: 84.9: 12.70		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1264774 TITIN_HUMAN (79-1153): 3.14e-15: 84.6: 10.07		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370263 MINT_HUMAN (76-1784): 4.28e-28: 126: 7.98		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369607 MDC1_HUMAN (508-1516): 4.61e-24: 113: 10.37		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370040 KMT2C_HUMAN (88-1775): 2.2e-16: 88.1: 7.78		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370103 ELYS_HUMAN (577-1779): 2.2e-15: 84.9: 12.70		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370105 TITIN_HUMAN (79-1153): 3.14e-15: 84.6: 10.07		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		782640 MINT_HUMAN (76-1784): 4.28e-28: 126: 7.98		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377624 MINT_HUMAN (76-1784): 4.28e-28: 126: 7.98		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		782595 KMT2C_HUMAN (88-1775): 2.2e-16: 88.1: 7.78		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377539 TITIN_HUMAN (79-1153): 3.14e-15: 84.6: 10.07		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377832 PRC2C_HUMAN (87-1452): 1.6e-12: 75.4: 8.27		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487431 MDC1_HUMAN (508-1516): 4.61e-24: 113: 10.37		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487596 KMT2C_HUMAN (88-1775): 2.2e-16: 88.1: 7.78		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59